Fluorescein angiography and optical coherence tomography concordance for choroidal neovascularisation in multifocal choroidtis. Issue 11 (14th May 2010)

• Record Type: Journal Article
• Authors: Kotsolis, Athanasios I; Killian, Frank A; Ladas, Ioannis D; Yannuzzi, Lawrence A
• Is Part Of: British journal of ophthalmology. Volume 94:Issue 11(2010)
• Page Start: 1506
• Page End: 1508
• Publication Date: 2010-05-14
• Subjects: Choroidal neovascularisation -- fluorescein angiography -- multifocal choroiditis -- optical coherence tomography -- choroid -- inflammation -- imaging; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.2009.159913
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Purpose: To compare the utility of fluorescein angiography (FA) and optical coherence tomography (OCT) as diagnostic adjuncts in evaluating symptomatic patients with choroidal neovascularisation (CNV) due to multifocal choroiditis (MFC). Methods: Patients with CNV due to MFC were retrospectively evaluated in a consecutive fashion. Fundus photography, FA, OCT and biomicroscopy were used to establish the diagnosis. Primary outcome measures included CNV classification (type 1 or occult and type 2 or classic) location and the associated FA and OCT findings. Results: Twenty eyes from 17 patients were included in the study. In 19 eyes (95%) the FA revealed CNV type 2; in one eye (5%) the type of CNV was indeterminate due to a subretinal haemorrhage that covered the lesion. Thirteen eyes had OCT imaging and all revealed hyper-reflectance beneath the neurosensory retina. However, only 53.8% revealed subretinal fluid (SRF) or intraretinal cystic abnormalities. Conclusions: The CNV in MFC is virtually always type 2, or so-called classic CNV, with vessels beneath the neurosensory retina. Except when blocked by subretinal blood, the neovascularisation is clearly demonstrated by FA. In contrast, only 53.8% of these eyes showed clear evidence of actively proliferating neovascularisation on OCT. Therefore, eyes suspected of having CNV in MFC should be evaluated with FA.