Haemophilus infection in cystic fibrosis. Issue 3 (March 1990)

• Record Type: Journal Article
• Authors: Rayner, R J; Hiller, E J; Ispahani, P; Baker, M
• Is Part Of: Archives of disease in childhood. Volume 65:Issue 3(1990)
• Page Start: 255
• Page End: 258
• Publication Date: 1990-03
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.65.3.255
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Twenty seven patients with cystic fibrosis under the age of 12 years and 27 matched patients with asthma were followed up in a prospective study for one year. The isolation rate of non-capsulated strains of Haemophilus influenzae from cough swabs and sputum specimens taken at routine clinic visits every two months was significantly greater in cystic fibrosis than in asthma. Haemophilus para-influenzae was equally common in both groups. During exacerbations the isolation rate of H influenzae in cystic fibrosis was significantly greater than at other times, whereas in asthma there was no significant difference. The distribution of biotypes of H influenzae and H parainfluenzae was similar in the two groups. In cystic fibrosis, biotype I was associated with exacerbations. Biotype V was more common than in previous studies, but was not associated with exacerbations.