Potential Impact of Male Circumcision, Condom Use, and Microbicides on the Dynamics of HIV/AIDS. (15th October 2012)

• Record Type: Journal Article
• Authors: Elias, Felix; Tchuenche, Jean M.
• Other Names: Foy B. Academic Editor.; Santillán M. Academic Editor.
• Is Part Of: ISRN biomathematics. Volume 2012(2012)
• Publication Date: 2012-10-15
• Subjects: Biomathematics -- Periodicals; Models, Biological; Biometry; Biomathematics; Electronic journals; Periodicals; Periodicals; Fulltext; Internet Resources; Periodicals; 570.151
• DOI: 10.5402/2012/516519
• Languages: English
• ISSNs: 2090-7702

Abstract

Abstract : HIV/AIDS remains an important global cause of morbidity and mortality. While medical male circumcision and condom and microbicides use hold great promise for helping to stem the tide of new HIV infections, theoretically providing further evidence of the potential long-term population-level benefit of their combined effects is viable. A deterministic sex-structured model is formulated, the expected lifetime disease reproductive output of an individual (or epidemiological birth) is determined, and the stability of steady states is investigated. To complement HIV treatment with antiretrovirals, which is not yet fully accessible to all those in need, microbicides and nontherapeutic measures such as male circumcision and condoms provide additional potential impact on curtailing the spread of HIV/AIDS.