Acute sensory and autonomic neuropathy: possible association with coxsackie B virus infection. Issue 7 (July 1992)

• Record Type: Journal Article
• Authors: Pavesi, G; Gemignani, F; Macaluso, G M; Ventrua, P; Magnani, G; Fiocchi, A; Medici, D; Marbini, A; Mancia, D
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 55:Issue 7(1992)
• Page Start: 613
• Page End: 615
• Publication Date: 1992-07
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.55.7.613
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : This report describes a 26 year old woman with a Coxsackie B virus infection complicated by an acute pandysautonomic and sensory neuropathy. Electrophysiological studies suggested an axonal neuropathy. A sural nerve biopsy performed early in the disease showed axonal degeneration with a virtual absence of unmyelinated fibres and moderate loss of myelinated fibres, mainly affecting the small fibres; this differs from previous reports. An immune-mediated or direct virus action might explain the pathogenesis of this unusual evolution of a viral infection.