Management of prolonged hypoglycaemia in Beckwith's syndrome. Issue 617 (March 1977)

• Record Type: Journal Article
• Authors: Moncrieff, M. W.; Lacey, K. A.; Malleson, P. N.
• Is Part Of: Postgraduate medical journal. Volume 53:Issue 617(1977)
• Page Start: 159
• Page End: 161
• Publication Date: 1977-03
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.53.617.159
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : A new-born baby with Beckwith's syndrome had severe hypoglycaemia, and was treated with glucagon and prednisone. Treatment was stopped at 1 month of age and his blood glucose levels were satisfactory for the ensuing 6 weeks. However, at 10 weeks of age, he had a hypoglycaemic convulsion and required large doses of diazoxide and prednisone for the next 2 months to maintain the blood glucose above 40 mg/100 ml. Insulin excretion was raised until he was 4 months old. Cases of Beckwith's syndrome which develop hypoglycaemia, should be treated with diazoxide and corticosteroids until insulin excretion is normal.