Complex partial status epilepticus associated with cyclosporin A therapy. Issue 9 (September 1989)

• Record Type: Journal Article
• Authors: Appleton, R E; Farrell, K; Teal, P; Hashimoto, S A; Wong, P K
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 52:Issue 9(1989)
• Page Start: 1068
• Page End: 1071
• Publication Date: 1989-09
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.52.9.1068
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Significant neurotoxicity including seizures, encephalopathy and coma may complicate the use of cyclosporin A (CyA). Two patients are described, receiving CyA, who presented with abnormal behaviour, stupor, focal motor activity and were shown to be in complex partial status epilepticus (CPSE). Abnormalities of behaviour and/or stupor in patients receiving CyA may be a manifestation of CPSE. Patients receiving CyA who develop an encephalopathy should have electroencephalography performed at the time of the abnormal behaviour.