Permeability of the small intestine to substances of different molecular weight. Issue 6 (June 1970)

• Record Type: Journal Article
• Authors: Loehry, C. A.; Axon, A. T. R.; Hilton, P. J.; Hider, R. C.; Creamer, B.
• Is Part Of: Gut. Volume 11:Issue 6(1970)
• Page Start: 466
• Page End: 470
• Publication Date: 1970-06
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.11.6.466
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : The permeability of the rabbit small intestine has been studied by measuring the plasma clearances of water-soluble molecules over the molecular weight range 60-33, 000. An inverse relationship has been demonstrated between permeability and molecular weight. The significance of these findings in relation to current concepts of the `pore hypotheses' is discussed, and the possible physiological and pathological implications are considered.