Guidelines for processing and reporting of prostatic needle biopsies. Issue 5 (1st May 2003)

• Record Type: Journal Article
• Authors: van der Kwast, Th H; Lopes, C; Santonja, C; Pihl, C-G; Neetens, I; Martikainen, P; Di Lollo, S; Bubendorf, L; Hoedemaeker, R F
• Other Names: group-author.
• Is Part Of: Journal of clinical pathology. Volume 56:Issue 5(2003)
• Page Start: 336
• Page End: 340
• Publication Date: 2003-05-01
• Subjects: prostate cancer -- needle biopsy -- histopathology -- tissue processing -- quality control; ERSPC, European Randomised Study of Screening for Prostate Cancer -- PIN, prostatic intraepithelial neoplasia -- PSA, prostate specific antigen; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.56.5.336
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The reported detection rate of prostate cancer, lesions suspicious for cancer, and prostatic intraepithelial neoplasia (PIN) in needle biopsies is highly variable. In part, technical factors, including the quality of the biopsies, the tissue processing, and histopathological reporting, may account for these differences. It has been thought that standardisation of tissue processing might reduce the observed variations in detection rate. Consensus among the members of the pathology committee of the European Randomised study of Screening for Prostate Cancer (ERSPC) concerning the optimal methodology of tissue embedding resulting in guidelines for prostatic needle biopsy processing was reached. The adoption of an unequivocal and uniform way of reporting lesions encountered in prostatic needle biopsies is considered helpful for decision taking by the clinician. The definition of parameters for quality control of prostatic needle biopsy diagnostics will further facilitate clinical epidemiological multicentre studies of prostate cancer.