Twenty years of pediatric diabetes surveillance: what do we know and why it matters. Issue 1 (5th February 2021)

• Record Type: Journal Article
• Authors: Dabelea, Dana; Sauder, Katherine A.; Jensen, Elizabeth T.; Mottl, Amy K.; Huang, Alyssa; Pihoker, Catherine; Hamman, Richard F.; Lawrence, Jean; Dolan, Lawrence M.; Agostino, Ralph D'; Wagenknecht, Lynne; Mayer‐Davis, Elizabeth J.; Marcovina, Santica M.
• Other Names: Ahima Rexford S. guestEditor.
• Is Part Of: Annals of the New York Academy of Sciences. Volume 1495:Issue 1(2021)
• Page Start: 99
• Page End: 120
• Publication Date: 2021-02-05
• Subjects: type 1 diabetes -- type 2 diabetes -- youth -- surveillance -- epidemiology -- health disparities; Medical sciences -- Periodicals; Medicine -- Periodicals; Science -- Periodicals; 610
• DOI: 10.1111/nyas.14573
• Languages: English
• ISSNs: 0077-8923

Abstract

Abstract: SEARCH for Diabetes in Youth (SEARCH) was initiated in 2000 as a multicenter study to address major gaps in the understanding of childhood diabetes in the United States. An active registry of youth diagnosed with diabetes at age <20 years since 2002 assessed prevalence, annual incidence, and trends by age, race/ethnicity, sex, and diabetes type. An observational cohort nested within the population‐based registry was established to assess the natural history and risk factors for acute and chronic diabetes‐related complications, as well as the quality of care and quality of life of children and adolescents with diabetes from diagnosis into young adulthood. SEARCH findings have contributed to a better understanding of the complex and heterogeneous nature of youth‐onset diabetes. Continued surveillance of the burden and risk of type 1 and type 2 diabetes is important to track and monitor incidence and prevalence within the population. SEARCH reported evidence of early diabetes complications highlighting that continuing the long‐term follow‐up of youth with diabetes is necessary to further our understanding of its natural history and to develop the most appropriate approaches to primary, secondary, and tertiary prevention of diabetes and its complications. This review summarizes two decades of research and suggests avenues for further work. Abstract : We provide a summary of the design and methods used, and an overview of major findings since the inception of the SEARCH for Diabetes in Youth Study in 2000. These include a summary of the risk, burden, and prognosis of diabetes diagnosed under the age of 20 years, with an emphasis on the disparities that were identified over these years. We also summarize morbidity and mortality information; patterns of, and barriers to, care of diabetes in youth; behavioral and social correlates; issues related to sustainable surveillance; and what the increase in young adults with diabetes who become parents implies.