Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation. (20th October 2011)

• Record Type: Journal Article
• Authors: Falkenberg, Susan Skanderup; Tarnow, Inge; Guzman, Alfonso; Mølgaard, Per; Simonsen, Henrik Toft
• Other Names: De Albuquerque Ulysses Paulino Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2012(2012)
• Publication Date: 2011-10-20
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2012/647620
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : 12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the ADP- (5.0 μ M) and collagen- (2.0 μ g/mL) induced aggregations in human blood. These four species in respective extracts (in brackets) were Blechnum chilense (MeOH), Luma apiculata (H2 O), Amomyrtus luma (DCM : MeOH 1 : 1) and Cestrum parqui (DCM : MeOH 1 : 1). The platelet aggregating inhibitory effects of A. luma (DCM : MeOH 1 : 1), and L. apiculata (H2 O) were substantial and confirmed by inhibition of platelet surface activation markers.