Intrapatellar tendon lipoma with chondro-osseous differentiation: detection of HMGA2-LPP fusion gene transcript. Issue 4 (27th March 2006)

• Record Type: Journal Article
• Authors: Matsui, Y; Hasegawa, T; Kubo, T; Goto, T; Yukata, K; Endo, K; Bando, Y; Yasui, N
• Is Part Of: Journal of clinical pathology. Volume 59:Issue 4(2006)
• Page Start: 434
• Page End: 436
• Publication Date: 2006-03-27
• Subjects: lipoma -- chromosomal translocation -- RT-PCR -- endochondral bone formation; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.2005.026393
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A 54 year old man developed an unusual lipoma in the patellar tendon, consisting of a fibro-adipose component and a chondro-osseous component. The fibro-adipose component contained mature adipocytes, lipoblasts, and fibroblasts; the chondro-osseous component showed typical endochondral bone formation. Molecular analysis showed that the identical HMGA2-LPP fusion transcript—characteristic of lipoma, parosteal lipoma, and pulmonary chondroid hamartoma—was detectable in the both components.