Neurogenic muscular atrophy and low density of large myelinated fibres of sural nerve in chorea-acanthocytosis. Issue 7 (July 1981)

• Record Type: Journal Article
• Authors: Ohnishi, A; Sato, Y; Nagara, H; Sakai, T; Iwashita, H; Kuroiwa, Y; Nakamura, T; Shida, K
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 44:Issue 7(1981)
• Page Start: 645
• Page End: 648
• Publication Date: 1981-07
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.44.7.645
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : In three cases of chorea-acanthocytosis (acanthocytosis and neurological disease, or familial degeneration of the basal ganglia with acanthocytosis), biopsies of short peroneal muscles and sural nerves were studied histologically. The muscles showed groups of atrophic fibres with clumping of sarcolemmal nuclei in all cases. It was concluded that neurogenic muscular atrophy should be included as one of the main pathological findings in chorea-acanthocytosis. The sural nerves showed a small number of large myelinated fibres in two cases. This finding remains to be confirmed in other cases.