Gastin cells and fasting gastrin levels in duodenal ulcer patients: a quantitative study based on multiple biopsy specimens. Issue 2 (February 1979)

• Record Type: Journal Article
• Authors: Piris, J; Whitehead, R
• Is Part Of: Journal of clinical pathology. Volume 32:Issue 2(1979)
• Page Start: 171
• Page End: 178
• Publication Date: 1979-02
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.32.2.171
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The number of gastrin-producing cells in biopsy specimens from the gastric and duodenal mucosae in 19 duodenal ulcer patients was quantitated using a morphometric method. The level of immunoreactive gastrin in a sample of fasting serum obtained at the time of the biopsy was measured by radioimmunoassay. The results show no significant difference when compared with those from a group of normal control volunteers. Moreover, there was no correlation between the numbers of gastrin-producing cells and the fasting serum gastrin level in either controls or duodenal ulcer patients.