Congenital hypoplasia of depressor anguli oris muscle: A genetically determined condition?. Issue 12 (December 1974)

• Record Type: Journal Article
• Authors: Papadatos, C.; Alexiou, D.; Nicolopoulos, D.; Mikropoulos, H.; Hadzigeorgiou, E.
• Is Part Of: Archives of disease in childhood. Volume 49:Issue 12(1974)
• Page Start: 927
• Page End: 931
• Publication Date: 1974-12
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.49.12.927
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : The frequency of hypoplasia of the depressor anguli oris muscle was 37 cases among 4 530 consecutive births (8·2%). Diagnosis was based on clinical and electromyographic studies. Severe congenital anomalies were detected in 3 of the 37 cases, while another 3 newborns had minor congenital defects. In 17 of the 37 cases there were first- or second-degree relatives with lower lip asymmetry. A minimum of 13 out of the 74 parents of the probands were affected. The high incidence of affection among first-degree relatives of the probands is strong evidence of hereditary factors playing a role in the aetiology of this anomaly.