Reassessment of the corneal endothelial cell organisation in children. Issue 7 (1st July 2000)

• Record Type: Journal Article
• Authors: Müller, Andreas; Doughty, Michael J; Wright, Lesley
• Is Part Of: British journal of ophthalmology. Volume 84:Issue 7(2000)
• Page Start: 692
• Page End: 696
• Publication Date: 2000-07-01
• Subjects: corneal endothelial cell organisation -- children; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.84.7.692
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : AIM: To assess uniformity of the corneal endothelial cell mosaic in children. METHODS: 36 healthy children (5–11 years old, 16 boys, 20 girls) were assessed by specular microscopy. Endothelial cell density (ECD) was calculated from measured cell areas, and the number of sides/cell noted. RESULTS: Average values for ECD and cell areas were 3987 cells/mm 2 (95% CI 3806 to 4168 cells/mm 2 ) and 278 (SD 85) μm 2 respectively, with normal distribution (COV 28.2%, range 17.4 to 39.2%) and with the average percentage of six sided cells being 66.6% (8.8%). Cell area was positively correlated to number of cell sides (p <0.01, r 2 =0.993), but the percentage of six sided cells was negatively correlated to ECD (p <0.01, r =0.493). CONCLUSION: A high ECD occurs in children, but this does not mean there is a high percentage of "hexagons".