Myopathy in Whipple's disease. Issue 10 (October 1977)

• Record Type: Journal Article
• Authors: Swash, M; Schwartz, M S; Vandenburg, M J; Pollock, D J
• Is Part Of: Gut. Volume 18:Issue 10(1977)
• Page Start: 800
• Page End: 804
• Publication Date: 1977-10
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.18.10.800
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : We report a patient with Whipple's disease who developed a myopathy that improved during antibiotic therapy. The muscle biopsy showed mild type 2 fibre atrophy, type 1 fibre preponderance, variability in fibre size, and changes in the myofibrillar pattern of affected fibres. Interfascicular macrophages contained PAS-positive material. With the electron microscope these macrophages contained membranous inclusions and bacillary bodies, similar to those seen in the jejunal biopsy.