Pseudomonas cepacia: a new pathogen in patients with cystic fibrosis referred to a large centre in the United Kingdom. Issue 8 (August 1990)

• Record Type: Journal Article
• Authors: Simmonds, E J; Conway, S P; Ghoneim, A T; Ross, H; Littlewood, J M
• Is Part Of: Archives of disease in childhood. Volume 65:Issue 8(1990)
• Page Start: 874
• Page End: 877
• Publication Date: 1990-08
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.65.8.874
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Pseudomonas cepacia infection has become increasingly common among patients with cystic fibrosis in North America. In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two of whom deteriorated rapidly shortly after acquisition of the organism despite intensive treatment with appropriate antibiotics. Analysis of possible causes of the increase in P cepacia infection suggested that neither patient to patient transmission nor the use of nebulised antibiotics was associated with an increased risk of infection.