Osteophytes and joint space narrowing are independently associated with pain in finger joints in hand osteoarthritis. Issue 10 (8th July 2011)

• Record Type: Journal Article
• Authors: Kortekaas, Marion C; Kwok, Wing-Yee; Reijnierse, Monique; Huizinga, Tom W J; Kloppenburg, Margreet
• Is Part Of: Annals of the rheumatic diseases. Volume 70:Issue 10(2011)
• Page Start: 1835
• Page End: 1837
• Publication Date: 2011-07-08
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.2010.147553
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Objective: To study the associations between structural abnormalities on ultrasound (US) or conventional x-rays (CR) and pain in hand osteoarthritis (HOA). Methods: In 55 consecutive patients with HOA (mean age 61 years, 86% women) fulfilling the American College of Rheumatology criteria, pain in 30 separate hand joints was assessed upon palpation; osteophytes were assessed by US and CR and joint space narrowing (JSN) by CR. Associations between structural abnormalities and pain per joint were analysed using generalised estimated equations to account for patient effects and adjusted for age, sex, body mass index, US inflammatory features and other remaining structural abnormalities. Results: In 1649 joints, 69% and 46% had osteophytes on US and CR, respectively and 47% had JSN. Osteophytes and JSN showed independent associations with pain per joint adjusted: OR for osteophytes: 4.8 (95% CI 3.1 to 7.5) for US and 4.1 (95% CI 2.4 to 7.1) for CR; for JSN: 4.2 (95% CI 2.0 to 9.0). Conclusions: Osteophytes and JSN are independently associated with pain in individual HOA joints, taking into account patient effects.