Bacterial antigens in synovial biopsy specimens in yersinia triggered reactive arthritis. Issue 2 (February 1991)

• Record Type: Journal Article
• Authors: Merilahti-Palo, R; Söderström, K O; Lahesmaa-Rantala, R; Granfors, K; Toivanen, A
• Is Part Of: Annals of the rheumatic diseases. Volume 50:Issue 2(1991)
• Page Start: 87
• Page End: 90
• Publication Date: 1991-02
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.50.2.87
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Non-viable structures of Yersinia enterocolitica O:3 were shown at the site of inflammation within mononuclear cells in the synovial membrane of eight out of 10 patients with yersinia triggered reactive arthritis. An avidin-biotin-peroxidase complex method, with a rabbit antiserum specific for Y enterocolitica O:3, was used to visualise yersinia structures. All 13 control samples were negative except for one with non-specific mast cell staining. The findings emphasise the significance of foreign material in the initiation of synovitis in reactive arthritis.