Mitomycin C for pterygium: long term evaluation. Issue 11 (15th October 2004)

• Record Type: Journal Article
• Authors: Raiskup, F; Solomon, A; Landau, D; Ilsar, M; Frucht-Pery, J
• Is Part Of: British journal of ophthalmology. Volume 88:Issue 11(2004)
• Page Start: 1425
• Page End: 1428
• Publication Date: 2004-10-15
• Subjects: MMC, mitomycin C; Mitomycin C -- pterygium; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.2003.039891
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Aim: To evaluate long term complications after pterygium excision with mitomycin C (MMC) application. Design: Prospective non-comparative interventional case series. Participants: Ninety nine patients who underwent pterygium surgery and participated in a controlled study for efficacy of MMC for pterygium surgery between 1989 and 1994. Methods: Patients who were located and agreed to come for examination underwent a complete eye examination. The bare sclera area, in particular, was examined for possible complications. The main outcome measures were anatomical findings in area of MMC application. Results: Forty three eyes of 43 patients were examined. Sixty three per cent of patients had pterygium surgery with intraoperative application of 0.02% MMC for 5 minutes and 37% of patients received MMC 1% or 2% drops four times daily for 2 weeks postoperatively. In three patients, pterygium recurred within 18 months. The only complication was mild conjunctival avascularity in areas of pterygium excision in 30% of patients. Conclusion: Long term evaluation revealed that the use of MMC in pterygium surgery is safe, but for a strict selection of patients, controlled use of MMC and long term follow up are required.