Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia. Issue 942 (13th April 2004)

• Record Type: Journal Article
• Authors: Vavricka, S R; Halter, J; Hechelhammer, L; Himmelmann, A
• Is Part Of: Postgraduate medical journal. Volume 80:Issue 942(2004)
• Page Start: 236
• Page End: 238
• Publication Date: 2004-04-13
• Subjects: Pneumocystic carinii pneumonia -- chronic lymphocytic leukaemia; Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.2003.012252
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : Pneumocystis carinii pneumonia in patients with chronic lymphocytic leukaemia (CLL) who have not been treated with fludarabin are rare, although clinically relevant CD4 T-cell depletion can occur in longstanding CLL without prior treatment with purine analogues. A 52 year old woman is reported who was on long term treatment with chlorambucil and taking a short course of prednisone for familial CLL before she developped progressive dyspnoea, and P carinii pneumonia was diagnosed in bronchoalveolar lavage fluid. Despite treatment with high dose co-trimoxazole the patient died.