Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis. Issue 5 (May 1976)

• Record Type: Journal Article
• Authors: Simon, M; Bourel, M; Fauchet, R; Genetet, B
• Is Part Of: Gut. Volume 17:Issue 5(1976)
• Page Start: 332
• Page End: 334
• Publication Date: 1976-05
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.17.5.332
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.