Neonatologists are using much less dexamethasone. Issue 5 (1st September 2003)

• Record Type: Journal Article
• Authors: Shinwell, E S; Karplus, M; Bader, D; Dollberg, S; Gur, I; Weintraub, Z; Arnon, S; Gottfreid, E; Zaritsky, A; Makhoul, I R; Reich, D; Sirota, L; Berger, I; Kogan, A; Yurman, S; Goldberg, M; Kohelet, D
• Is Part Of: Archives of disease in childhood. Volume 88:Issue 5(2003)
• Page Start: F432
• Page End: F433
• Publication Date: 2003-09-01
• Subjects: dexamethasone -- corticosteroids -- preterm -- chronic lung disease; Infants -- Diseases -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.920105
• DOI: 10.1136/fn.88.5.F432
• Languages: English
• ISSNs: 1359-2998

Abstract

Abstract : Two historical cohorts (1993–1994 and 2001) of preterm infants ventilated for respiratory distress syndrome were compared. Dexamethasone administration fell from 22% to 6%. Chronic lung disease in survivors rose slightly from 13% to 17%, and mortality fell from 21% to 15% (other causes). The effect of restriction of dexamethasone use on chronic lung disease and mortality remains to be seen.