Adhesion of rheumatoid peripheral blood and synovial fluid mononuclear cells to high endothelial venules of gut mucosa. Issue 1 (January 1992)

• Record Type: Journal Article
• Authors: Kadioglu, A; Sheldon, P
• Is Part Of: Annals of the rheumatic diseases. Volume 51:Issue 1(1992)
• Page Start: 126
• Page End: 127
• Publication Date: 1992-01
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.51.1.126
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Mononuclear cells isolated from paired blood and synovial fluid of seven patients with rheumatoid arthritis showed cytoadherence to porcine Peyer's patch high endothelial venules using the Stamper-Woodruff method. A significantly greater proportion of binding was found among the synovial fluid lymphocytes. These would appear to be a population of cells that share adherence characteristics with cells known to be of gut mucosal origin, suggesting that in rheumatoid arthritis some lymphocytes derived from mucosa migrate to joints.