Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge", Napoli, December 5th 2015. Issue 1 (18th October 2016)

• Record Type: Journal Article
• Authors: Ascierto, Paolo A.; Ascierto, Maria Libera; Formenti, Silvia; Gnjatic, Sacha; Hammers, Hans; Hirsh, Vera; Kiessling, Rolf; Melero, Ignacio; Nanda, Rita; Pawelec, Graham; Pignata, Sandro; Romero, Pedro; Speiser, Daniel E.; Fox, Bernard A.; Marincola, Francesco M.
• Is Part Of: Journal for immunotherapy of cancer. Volume 4:Issue 1(2016)
• Publication Date: 2016-10-18
• Subjects: Melanoma -- Ipilimumab -- Autologous Stem Cell Transplant -- Renal Cell Cancer -- Immune Checkpoint; Cancer -- Immunotherapy -- Periodicals; Cancer -- Immunological aspects -- Periodicals; Tumors -- Immunological aspects -- Periodicals; Immunotherapy -- Periodicals; 616.99406105
• DOI: 10.1186/s40425-016-0168-3
• Languages: English
• ISSNs: 2051-1426

Abstract

Abstract : Harnessing the immune system and preventing immune escape, the immunotherapy of cancer provides great potential for clinical application, in broad patient populations, achieving both conventional and unconventional clinical responses. After the substantial advances in melanoma, the focus of cancer immunotherapy has expanded to include many other cancers. Targeting immune checkpoints and further mechanisms used by tumors to avoid anticancer immunity, different approaches are under evaluation, including combination therapies. The first Immunotherapy Bridge meeting focused on various cancer types including melanoma, non-small cell lung cancer, renal cell, breast and ovarian carcinoma, and discussed mechanisms of action of single agents and combination strategies, and the prediction of clinical responses.