Randomised double-blind trial of bromovinyldeoxyuridine (BVDU) and trifluorothymidine (TFT) in dendritic corneal ulceration. Issue 11 (November 1991)

• Record Type: Journal Article
• Authors: Power, W. J.; Benedict-Smith, A.; Hillery, M.; Brady, K.; Collum, L. M.
• Is Part Of: British journal of ophthalmology. Volume 75:Issue 11(1991)
• Page Start: 649
• Page End: 651
• Publication Date: 1991-11
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.75.11.649
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : The results of a randomised double-blind clinical trial of 0.1% bromovinyldeoxyuridine (BVDU) and 1% trifluorothymidine (TFT) in 60 patients with corneal dendritic ulceration are presented. There was no significant difference between BVDU and TFT in terms of numbers of ulcers healed (p = 0.61), mean healing time (p = 0.065), and cumulative healing rate (p = 0.058). No serious side effects were observed, though transient stinging was recorded in five patients receiving TFT and in three patients receiving BVDU. One patient in the group treated with TFT developed a punctate epitheliopathy.