A double blind trial of botulinum toxin "A" in torticollis, with one year follow up. Issue 9 (September 1991)

• Record Type: Journal Article
• Authors: Moore, A P; Blumhardt, L D
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 54:Issue 9(1991)
• Page Start: 813
• Page End: 816
• Publication Date: 1991-09
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.54.9.813
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : A double blind placebo controlled crossover trial was performed of botulinum toxin "A" in 20 patients with spasmodic torticollis. There was a statistically significant benefit for those treated with toxin; 12 on toxin improved objectively, compared with four on placebo (p less than 0.04). After a follow up period of one year, 16 still seemed to benefit from repeated toxin injections. The main side effect was dysphagia, which appeared to be dose related in individual patients.