Advances in our understanding of the pathology of chronic intestinal pseudo-obstruction. Issue 11 (11th October 2004)

• Record Type: Journal Article
• Authors: De Giorgio, R; Sarnelli, G; Corinaldesi, R; Stanghellini, V
• Is Part Of: Gut. Volume 53:Issue 11(2004)
• Page Start: 1549
• Page End: 1552
• Publication Date: 2004-10-11
• Subjects: ANNA-1, antineuronal nuclear antibodies -- BCL-2, B cell lymphoma-2 -- CIP, chronic intestinal pseudo-obstruction -- CIIP, chronic intestinal idiopathic pseudo-obstruction -- ICC, interstitial cells of Cajal -- ENS, enteric nervous system; enteric nervous system -- enteric neuromyopathies -- interstitial cells of Cajal -- laparoscopy; Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.2004.043968
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Chronic intestinal pseudo-obstruction (CIP) represents a particularly difficult clinical challenge. It is a rare and highly morbid syndrome characterised by impaired gastrointestinal propulsion together with symptoms and signs of bowel obstruction in the absence of any lesions occluding the gut lumen. CIP can be classified as either "secondary" to a wide array of recognised pathological conditions or "idiopathic" (CIIP). This review will focus on CIIP, and specifically on the underlying pathological abnormalities. Combined clinical and histopathological studies are needed to highlight new perspectives in the understanding and management of chronic intestinal pseudo-obstruction.