Proteomics in cancer research. Issue 5 (1st August 2002)

• Record Type: Journal Article
• Authors: Wu, W.; Hu, W.; Kavanagh, J. J.
• Is Part Of: International journal of gynecological cancer. Volume 12:Issue 5(2002)
• Page Start: 409
• Page End: 423
• Publication Date: 2002-08-01
• Subjects: proteomics -- clinical application -- cancer; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-00009577-200209000-00001
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : With the human genome sequence now determined, the field of molecular medicine is moving beyond genomics to proteomics. In the field of cancer research, the key question is: how can oncologists best use techniques of proteomics in basic research and clinical application? In the postgenomic era, proteomics promises the discovery of biomarkers and tumor markers for early detection and diagnosis, novel protein-based drug targets for anticancer therapy, and new endpoints for the assessment of therapeutic efficacy and toxicity. This review paper will explore key themes in proteomics and their application in clinical cancer research.