Benefits and risks of folic acid to the nervous system. Issue 5 (1st May 2002)

• Record Type: Journal Article
• Authors: Reynolds, E H
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 72:Issue 5(2002)
• Page Start: 567
• Page End: 571
• Publication Date: 2002-05-01
• Subjects: folic acid -- nervous system -- benefits and risks; SAM, S-adenosylmethionine; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.72.5.567
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : During three decades of neurological practice I have witnessed a remarkable change in attitudes to the benefits and risks of folic acid therapy in nervous system disorders. In the 1960s all that was known and taught was that folic acid was harmful to the nervous system, especially in precipitating or exacerbating the neurological complications of vitamin B12 deficiency. So deeply held was this view that the possibility of neuropsychological benefits from this vitamin was initially viewed with considerable scepticism. 1