Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients. Issue 1 (January 1984)

• Record Type: Journal Article
• Authors: Murray, J A; Slater, D N; Parsons, M A; Fox, M; Smith, S; Platts, M M
• Is Part Of: Journal of clinical pathology. Volume 37:Issue 1(1984)
• Page Start: 59
• Page End: 64
• Publication Date: 1984-01
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.37.1.59
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The histological features of 40 spleens surgically removed from maintenance haemodialysis patients are reported. Twenty-four of the 40 (60%) showed massive iron loading and a significant direct correlation was found between iron loading and the amount of intravenous iron dextran administered. Since parenteral iron dextran appears to be a major factor in causing iron overload in haemodialysis patients its use as a method of iron replacement in these patients would appear inappropriate.