GP221 Influence of controlled physical activity on serum adipokines concentration in obese children. (June 2019)

• Record Type: Journal Article
• Authors: Wasilewska, Anna; Protas, Piotr; Rybi-Szuminska, Agnieszka; Taranta-Janusz, Katarzyna; Stelmach, Marian; Kuroczycka-Saniutycz, Elżbieta; Lemiesz, Marta
• Is Part Of: Archives of disease in childhood. Volume 104:(2019)Supplement 3
• Page Start: A120
• Page End: A120
• Publication Date: 2019-06
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/archdischild-2019-epa.280
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Introduction: The number of obese people is increasing, and its negative impact on the people's health is significant. The relationship between physical activity and obesity is still under investigation. One of components responsible for the metabolism are adipokines such as adropin or adiponectin. The purpose of this study was to investigate, whether the controlled physical activity affects the concentrations of adipokines and may play role in treatment of obesity in children. Material and Methods: 34 obese children aged 5–18 years were involved to the dynamic prospective study. The reference group consisted of 16 healthy children. The participants were informed about recommended physical activity, adjusted for sex, age, and degree of overweight. They were equipped with exercise recorder for a period of 8 weeks. Before start of the study and after 8 weeks of effort, has been made anthropometric measurements, electrical bioimpedance and blood serum was collected. Adropin and adiponectin concentrations in serum were determined by ELISA. Results: In the study group, 22 children decreased BMI Z-score. Average BMI Z-score has decreased from 2.75±0.43 at baseline to 2.51±0.31 at the end of the study (p<0.05). In the whole study group, there was no statistical significant differences in the concentrations of adiponectin and adropin compared between study points and the control group. In contrast, significantly increase the concentration of adropin after 8 weeks, in group of patients who have lowered their BMI Z-Score (38.84±20.29 vs. 64.54±40.45 pg/ml, p<0.01). Conclusions: Controlled physical activity leads to reduction of obesity in children and increases serum adropine concentration, which may play role in prevention of obesity complications.