AB1054 The Burden of Systemic Lupus Erythematosus on Patient's Occupational Activities. (15th July 2016)

• Record Type: Journal Article
• Authors: Sadovici-Bobeica, V.; Salaru, V.; Mazur-Nicorici, L.; Cebanu, M.; Pasali, M.; Mazur, M.
• Is Part Of: Annals of the rheumatic diseases. Volume 75(2016)Supplement 2
• Page Start: 1262
• Page End: 1262
• Publication Date: 2016-07-15
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2016-eular.2048
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Objectives: To determine the burden on systemic lupus erythematosus (SLE) on patient's occupational activities Methods: We conducted a cross-sectional study of SLE patients, fulfilling SLICC/ACR 2012 classification criteria. All patients were assessed for disease activity by SLEDAI, damage index by SLICC/ACR DI, general assessments by PGA and MGDA. We collected data on work activity using the Work Productivity Activity Impairment (WPAI) questionnaire for lupus patients. All patients completed the SF-8 questionnaire, estimating physical and mental component summaries (PCS and MCS) of the quality of life (QoL). Results: The study included 102 SLE patients, 94, 1% females, mean age ±SD 42, 4±13, 3 (range 20–73) years, mean disease duration±SD 93, 9±77, 1 (range 0, 1–228) months. A proportion of 34, 3% of the patients had high university education. The employment history in our cohort included: 23, 5% of subjects were working full time and 3, 9% part time. Meantime, 58, 8% of patients had disability for SLE and 6, 9% - disability for other disease than SLE; 3, 9% of the subjects were studying and 2% were not employed at the moment of the questionning. The results of WPAI questionnaire confirmed a dicrease of all work domains, by absenteism (10%) and presenteism (63.4%). To be noticed that 20 from 28 working subjects were missing from their work during last 12 months during 15, 3 days (range 5–40 days) for SLE problems. The analysis of the QoL showed a dicrease of both components, PCS and MCS were 43, 2±9, 6 and 46, 9±13, 4 points, respectively. According to the results, the level of the QoL and the disease activity were predictors for impaired work productivity (R 2 =0.21 and R 2 =0.5, p<0.05). Conclusions: Systemic lupus erythematosus had a substantial burden on patient's occupational activities, high disease activity and low indices of the quality of life were predictors for impaired work productivity. Disclosure of Interest: None declared