Can patients with McArdle's disease run?. Issue 1 (25th September 2006)

• Record Type: Journal Article
• Authors: Pérez, M; Moran, M; Cardona, C; Maté-Muñoz, J L; Rubio, J C; Andreu, A L; Martin, M A; Arenas, J; Lucia, A
• Is Part Of: British journal of sports medicine. Volume 41:Issue 1(2007)
• Page Start: 53
• Page End: 54
• Publication Date: 2006-09-25
• Subjects: Sports medicine -- Periodicals; 617.1027
• DOI: 10.1136/bjsm.2006.030791
• Languages: English
• ISSNs: 0306-3674

Abstract

Abstract : Patients with McArdle's disease commonly adopt a sedentary lifestyle. This sedentary behaviour, however, usually worsens the limited exercise capacity of these patients. Although eccentric muscle work can be associated with rhabdomyolysis, supervised eccentric training with gradually increasing loads has important advantages compared with conventional concentric work, particularly for patients with a poor cardiorespiratory system. We report the beneficial effects (particularly, increased VO2peak (from 14.6 to 30.8 ml/kg/min) and increased gross muscle efficiency (from 13.8% to 17.2%)) induced by a supervised aerobic training programme of 7 months duration including 3–4 running sessions (⩽60 min/session) per week in a 38-year-old patient. These preliminary data suggest the potential therapeutic value of this type of exercise in these patients.