Role of MRI perfusion in improving the treatment of brain tumors. (October 2013)

• Record Type: Journal Article
• Authors: Fussell, David; Young, Robert J
• Is Part Of: Imaging in medicine. Volume 5:Number 5(2013)
• Page Start: 407
• Page End: 426
• Publication Date: 2013-10
• Subjects: arterial spin-labeled -- brain tumors -- dynamic contrast-enhanced -- dynamic susceptibility contrast -- MRI perfusion -- pseudoprogression -- pseudoresponse -- radiation injury; Diagnostic imaging -- Periodicals; 616.075405
• DOI: 10.2217/iim.13.50
• Languages: English
• ISSNs: 1755-5205

Abstract

The goal of MRI perfusion is to provide noninvasive estimates of functional hemodynamic parameters. The purpose of this article is to review commonly used perfusion techniques: arterial spin-labeled, dynamic susceptibility-weighted contrast and dynamic contrast-enhanced imaging. The advantages, disadvantages and limitations of each technique are discussed. Specific applications in tumor imaging are discussed in terms of determining tumor diagnosis, prognosis and treatment failure versus response.