Genetic diversity and phylogenetic analyses of hui and Kazakh populations in northwest of China via 15 autosomal STR loci. Issue 1 (December 2019)

• Record Type: Journal Article
• Authors: Zheng, Yuzi; Ye, Yi; Cao, Gang; Fan, Guangyao; Tian, Chenchen; Cui, Xuejun; Jiang, Lanrui; Liao, Linchuan
• Is Part Of: Forensic science international. Volume 7:Issue 1(2019)
• Page Start: 652
• Page End: 654
• Publication Date: 2019-12
• Subjects: Genetic diversity -- Autosomal STR -- Hui -- Kazakh; Forensic genetics -- Periodicals; Forensic Genetics -- Periodicals; Electronic journals; 614.1
• DOI: 10.1016/j.fsigss.2019.10.126
• Languages: English
• ISSNs: 1875-1768

Abstract

Abstract: In the present study, genetic polymorphisms of 15 autosomal STR loci were obtained from 185 unrelated healthy individuals (86 Hui and 99 Kazakh). No evidence of deviation from the Hardy-Weinberg equilibrium (HWE) was identified after applying the Bonferroni correction. The combined power of discrimination (CDP) and combined power of exclusion (CPE) of the 15 STR loci in Hui and Kazakh population were both larger than 0.99999999999999995 and 0.9999973, respectively. A Neighbor-Joining (NJ) phylogenetic tree was constructed based on allelic frequencies. It exhibited the closeness of the Hui and Kazakh with the Uyghur. Results suggested that the 15 STR loci had a relatively high genetic variation, which can be utilized for forensic personal identification and paternity testing in Hui and Kazakh population.