AB0655 Cross-Cultural Adaptation and Validation of The Behçet's Syndrome Activity Score (BSAS) to Brazilian Portuguese Language: Strong Correlation with Brazilian Behçet's Disease Current Activity form (BR-BDCAF). (9th June 2015)

• Record Type: Journal Article
• Authors: Colman, O.G.; Prado, L.L.; Saad, C.G.S.; Levy-Neto, M.; Gonçalves, C.R.
• Is Part Of: Annals of the rheumatic diseases. Volume 74(2015)Supplement 2
• Page Start: 1117
• Page End: 1118
• Publication Date: 2015-06-09
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2015-eular.2143
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Assessment of Behçet's Syndrome (BS) activity has been a concern since a treat-to-target strategy may improve disease outcome. The Brazilian Behçet's Disease Current Activity Form (BR-BDCAF) is currently validated for Brazilian Portuguese, however, it is completed by the physician. Developed originally in English, the Behçet's Syndrome Activity Score (BSAS) is the first patient-reported assessment tool, which would be useful in clinical routine use and clinical trial evaluations. Objectives: To perform a cross-cultural adaptation of the BSAS to Brazilian Portuguese language and to evaluate its reliability in a population of Brazilian patients with BS, comparing to BR-BDCAF as a gold standard pattern. Methods: Brazilian Portuguese version of the BSAS, named BR-BSAS, was obtained according to established guidelines. Fifty-five BS patients, diagnosed according to the International Study Group for Behçet's Disease criteria, were requested to complete the BR-BSAS. A rheumatologist performed the BR-BDCAF on the same visit. Fifteen patients were selected for a second visit two weeks later, and completed the BR-BSAS once again. Descriptive statistics, intraclass correlation coefficient, internal consistency were calculated to assess reliability and validity of BR-BSAS. Also, we used Pearson coefficient to analyze correlation between the two questionnaires (BR-BSAS and BR-BDCAF). Results: In this study group, 65.3% were females, with a mean age of 45.6 (SD 13.0) years and a mean disease duration of 15.9 (SD 13.0) years. The test-retest reliability of BSAS presented a good level (ICC=0.839, 95% CI [0.596-0.943]). Internal consistency was also acceptable, with a Cronbach's alpha of 0.773. Mean BR-BSAS score (range 0-100) was 31, 29 (SD 24, 54) and mean BR-BDCAF score (range 0-12) was 3, 41 (SD 2, 34). A strong correlation between BR-BSAS and BR-BDCAF scores was found (r=0.750). Conclusions: BR-BSAS may be used to assess disease activity in Brazilian BS patients, with a strong correlation between BR-BSAS and BR-BDCAF scores. As a self-reported measure, BR-BSAS may easier to use in clinical practice, adding a patient-derived outcome that may help to improve therapy management decision. Disclosure of Interest: None declared