Acute Ischaemic Stroke Cooperation Group of Endovascular Treatment (ANGEL) registry: study protocol for a prospective, multicentre registry in China. Issue 1 (19th March 2019)

• Record Type: Journal Article
• Authors: Huo, Xiaochuan; Ma, Ning; Mo, Dapeng; Gao, Feng; Yang, Ming; Wang, Yilong; Wang, Yongjun; Miao, Zhongrong
• Other Names: author non-byline.; Miao Zhongrong author non-byline.; Wang Yilong author non-byline.; Liu Liping author non-byline.; Zhao Xingquan author non-byline.; Wang Yongjun author non-byline.; Huo Xiaochuan author non-byline.; Liao Xiaoling author non-byline.; Wang Chunjuan author non-byline.; Yang Ming author non-byline.; Peng Ya author non-byline.; Chen Wenhuo author non-byline.; Chen Shengli author non-byline.; Song Cunfeng author non-byline.; Gao Lianbo author non-byline.; Wang Shouchun author non-byline.; Zhu Qiyi author non-byline.; Yang Hua author non-byline.; Zhao Deqiang author non-byline.; Li Tong author non-byline.; Jing Ping author non-byline.; Zhao Junfeng author non-byline.; Wei Liping author non-byline.; Gui Liqiang author non-byline.; Shi Hongchao author non-byline.; Tu Mingyi author non-byline.; Ye Huawei author non-byline.; Xu Xiaohui author non-byline.; Feng Xie author non-byline.; Pan Anxin Wang，yuesong author non-byline.; Zhang Xiaoli author non-byline.; Meng Xia author non-byline.; Wang Yilong author non-byline.; Liu Gaifen author non-byline.; Zhang Xiaoli author non-byline.; Xu Anding author non-byline.; Feng Lei author non-byline.; Yu Wengui author non-byline.; Gao Peiyi author non-byline.;
• Is Part Of: Stroke and vascular neurology. Volume 4:Issue 1(2019)
• Page Start: 57
• Page End: 60
• Publication Date: 2019-03-19
• Subjects: acute ischemic stroke -- mechanical thrombectomy -- endovascular therapy; Cerebrovascular disease -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.81005
• DOI: 10.1136/svn-2018-000188
• Languages: English
• ISSNs: 2059-8688

Abstract

Abstract : Background and purpose: Endovascular treatment could improve functional outcomes and reduce mortality in patients with intracranial large artery occlusion. This registry aims to evaluate the endovascular treatment delivery and to improve endovascular treatment algorithm in clinical practice for patients with stroke in China. Methods and analysis: This multicentric, nationwide, prospective registry plans to include 20 stroke centres and recruit 900 consecutive AIS patients with large-artery occlusion under endovascular treatment. This registry will enrol acute large vessel occlusion patients suitable for endovascular treatment and the inclusion and exclusion criteria. In this study, 90 days functional independence (modified Rankin Scale score ≤2) is the primary efficacy endpoint. The procedural efficacy endpoint of this registry is target artery recanalisation defined by modified Thrombolysis in Cerebral Infarction score 2b or 3 after endovascular therapy. Symptomatic intracranial haemorrhage with 24±3 hours after the procedure is the primary safety endpoint of this registry. Ethics and dissemination: Beijing Tiantan Hospital's Ethics committee and all other participating centres approved the protocol and data collection of Acute Ischaemic Stroke Cooperation Group of Endovascular Treatment registry. Each participant or representative had a written informed consent.