UniQ-Typer ™ Y-10 genotyping in South African populations: novel alleles, sequence variation and allelic ladder updates. Issue 1 (December 2019)

• Record Type: Journal Article
• Authors: Kasu, Mohaimin; Fraser, Mischa; D'Amato, Maria Eugenia
• Is Part Of: Forensic science international. Volume 7:Issue 1(2019)
• Page Start: 473
• Page End: 475
• Publication Date: 2019-12
• Subjects: Forensic genetics -- Periodicals; Forensic Genetics -- Periodicals; Electronic journals; 614.1
• DOI: 10.1016/j.fsigss.2019.10.056
• Languages: English
• ISSNs: 1875-1768

Abstract

Abstract: DNA profiling the male specific region on the Y-chromosome is fundamental to forensic practise. It is recognised as a powerful tool for sexual assault investigations for resolving the male DNA components, for familial search and as a tool to aid biogeographic inferences. In this study the novel Y-chromosome Short Tandem Repeat (Y-STR) multiplex called the UniQ-Typer ™ Y-10 was utilised for population wide genotyping in South Africa. In this study we provide a significant updated to the genotyping allelic ladder for the panel and report novel variation which gave strong signals to potentially infer biogeographic ancestry.