Hemiballism-hemichorea and non-ketotic hyperglycaemia. Issue 6 (June 1994)

• Record Type: Journal Article
• Authors: Lin, J J; Chang, M K
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 57:Issue 6(1994)
• Page Start: 748
• Page End: 750
• Publication Date: 1994-06
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.57.6.748
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Three patients with hemiballism-hemichorea caused by non-ketotic hyperglycaemia are presented, two of whom had hyperosmolar non-ketotic hyperglycaemic syndrome. In two of the three patients, the hyperkinesia was the initial presenting symptom of their diabetes mellitus. The hypersensitivity of the postmenopausal dopamine receptor, decreased gamma-aminobutyric acid in the brain in non-ketotic hyperglycaemia, coexisting lacunar infarct in the basal ganglion, and pre-existing metabolic dysfunction in the basal ganglion may all have played a part in the pathogenesis of this movement disorder.