Reasons for Improved Survival From Ovarian Cancer in New South Wales, Australia, Between 1980 and 2003: Implications for Cancer Control. Issue 4 (1st April 2009)

• Record Type: Journal Article
• Authors: Tracey, Elizabeth A.; Roder, David M.; Francis, Jane; Zorbas, Helen M.; Hacker, Neville F.; Bishop, James F.
• Is Part Of: International journal of gynecological cancer. Volume 19:Issue 4(2009)
• Page Start: 591-599
• Page End: 591-599
• Publication Date: 2009-04-01
• Subjects: Ovarian cancer -- Survival -- Stage -- Histological type; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1111/IGC.0b013e3181a3a436
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : We analyzed New South Wales Central Cancer Registry data for 1980-2003, to determine time trends in case fatality from ovarian cancer, after adjusting for stage, histological, and sociodemographic factors, and to consider service-delivery and research implications. After adjusting for covariates, the relative risk (95% confidence limit) of ovarian-cancer death reduced to 0.51 (0.46, 0.57) for 1999-2003 compared with 1980-1983. Relative risks were higher for adenocarcinomas and other specified and unspecified cancers than serous carcinomas, but lower for endometrioid carcinomas, sex cord-stromal and germ cell tumors. The probability of diagnosis with localized as opposed to more advanced disease was lower in older patients, the lowest socioeconomic stratum, women born in non-English-speaking countries, and more recent diagnostic periods. Approximately 61% of ovarian cancers had distant metastases at diagnosis in 1999-2003. Poorer survivals apply to older patients. Research directed at finding an effective screening test for epithelial ovarian cancer remains a priority.