24-h sleep deprivation impairs early attentional modulation of neural processing: An event-related brain potential study. (11th June 2018)

• Record Type: Journal Article
• Authors: Wiggins, Eve; Mottarella, Malayka; Good, Kendra; Eggleston, Seth; Stevens, Courtney
• Is Part Of: Neuroscience letters. Volume 677(2018)
• Page Start: 32
• Page End: 36
• Publication Date: 2018-06-11
• Subjects: Sleep deprivation -- Selective attention -- attention -- Event-related brain potentials -- ERPs; Neurology -- Periodicals; Neurology -- Periodicals; Research -- Periodicals; Neurologie -- Périodiques; Neuroanatomie -- Périodiques; Neuropharmacologie -- Périodiques; Neurophysiologie -- Périodiques; Neurology; Periodicals; Electronic journals; 617.48
• DOI: 10.1016/j.neulet.2018.04.022
• Languages: English
• ISSNs: 0304-3940

Abstract

Highlights: Participants randomly assigned to regular sleep or 24-h sleep deprivation. ERPs recorded during a dichotic listening, selective attention task. Regular sleep participants showed typical attentional enhancement of the N1. Sleep deprived participants showed significantly reduced, and absent, N1 modulation. 24-h sleep deprivation impairs the earliest stages of attentional modulation. Abstract: Prior research indicates sleep deprivation negatively impacts selective attention, although less is known about the neural bases of these effects. The present study used event-related brain potentials (ERPs) to examine whether the effects of total sleep deprivation could be traced to the earliest stages of sensory processing influenced by selective attention. Participants were randomly assigned either to a regular sleep or 24-h total sleep deprivation condition. Following either sleep deprivation or regular sleep, participants completed a dichotic listening selective attention task while ERPs were acquired. Well-rested participants showed typical attentional modulation of the N1 between 150 and 250 msec, with larger amplitude responses to attended relative to unattended auditory probes. In contrast, these effects were significantly reduced in sleep-deprived participants, who did not show significant effects of selective attention on early neural processing. Similar group differences were observed in the later processing negativity, from 300 to 450 msec. Taken together, these results indicate that 24-h total sleep deprivation can significantly reduce, or eliminate, early effects of selective attention on neural processing.