Monozygotic twins discordant for rubinstein-taybi syndrome. Issue 4 (August 1981)

• Record Type: Journal Article
• Authors: Kajii, T; Hagiwara, K; Tsukahara, M; Nakajima, H; Fukuda, Y
• Is Part Of: Journal of medical genetics. Volume 18:Issue 4(1981)
• Page Start: 312
• Page End: 314
• Publication Date: 1981-08
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.18.4.312
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : A pair of male monozygotic twins discordant for Rubinstein-Taybi syndrome is reported. Monozygosity of the twins was established using blood grouping, typing of serum proteins, isozymes, HLA, and chromosomal heteromorphisms. The twins are the first twin pair discordant for the syndrome in which monozygosity has been firmly established. The pathogenesis of the syndrome is discussed in relation to the occurrence of both discordant and concordant monozygotic twins.