A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial. Issue 12 (December 1982)

• Record Type: Journal Article
• Authors: Gibberd, FB; Park, DM; Scott, G; Gawel, MJ; Fry, DE; Page, NGR; Engler, C; English, JR; Rose, F Clifford
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 45:Issue 12(1982)
• Page Start: 1113
• Page End: 1118
• Publication Date: 1982-12
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.45.12.1113
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : A double-blind cross-over trial between pheneturide and phenytoin in ninety-four outpatients with epilepsy is described. There was no significant difference between the frequency of seizures in the two groups. The difficulties in comparing two anticonvulsants of similar efficacy are discussed particularly in relation to ethical problems, the selection of patients and trial design.