Glycoproteins in cystic fibrosis: a lectin binding study. Issue 6 (December 1984)

• Record Type: Journal Article
• Authors: Karlsson, S; Griffiths, B; Swallow, D M; Hopkinson, D A; Wallis, P G
• Is Part Of: Journal of medical genetics. Volume 21:Issue 6(1984)
• Page Start: 441
• Page End: 446
• Publication Date: 1984-12
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.21.6.441
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : Ten lectins have been used to detect glycoproteins, after SDS polyacrylamide gel electrophoresis and gel isoelectric focusing, in fibroblasts, red cell membranes, urine, and plasma of patients and obligate heterozygotes with cystic fibrosis. No disease specific changes were detected but considerable individual variation was observed, some of which was attributed to known genetic polymorphisms unrelated to cystic fibrosis.