Juvenile Parkinsonism: clinical and metabolic characteristics. Issue 3 (March 1987)

• Record Type: Journal Article
• Authors: Lima, B; Neves, G; Nora, M
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 50:Issue 3(1987)
• Page Start: 345
• Page End: 348
• Publication Date: 1987-03
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.50.3.345
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Twenty one patients with idiopathic Parkinsonism beginning before the age of 40 years were investigated. The mean duration of the disease was 19 years. There was a good and sustained response to levodopa. Only four patients reached stages IV and V (Hoehn and Yahr). Intolerance to levodopa was observed in the more advanced stages of the disease. In the series the familial incidence of Parkinsonism (2 cases) and essential tremor (3 cases) was very low. Thyroid disorder, diabetes mellitus or macrocytic anaemia was not found in any of the cases.