A case of suspected teratogenic holoprosencephaly. Issue 2 (April 1985)

• Record Type: Journal Article
• Authors: Stabile, M; Bianco, A; Iannuzzi, S; Buonocore, M C; Ventruto, V
• Is Part Of: Journal of medical genetics. Volume 22:Issue 2(1985)
• Page Start: 147
• Page End: 149
• Publication Date: 1985-04
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.22.2.147
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : A case of holoprosencephaly is reported in which the mother was prescribed high doses of oestroprogestins during the first 5 months of the pregnancy. Investigation of the family failed to reveal any sign of physical abnormality. A normal karyotype was detected in the proband. The authors suggest that this case may shed some light on the normal and abnormal way in which embryonic fields develop.