Selective IgA deficiency with 18q+ and 18q-- karyotypic anomalies. Issue 6 (December 1980)

• Record Type: Journal Article
• Authors: Lewkonia, R M; Lin, C C; Haslam, R H
• Is Part Of: Journal of medical genetics. Volume 17:Issue 6(1980)
• Page Start: 453
• Page End: 456
• Publication Date: 1980-12
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.17.6.453
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : A case is described of selective immunoglobulin A deficiency in association with an 18q+ anomaly, apparently the result of a break at 18q23 and a de novo translocation. The presentation is compared with the phenotypic and immunological features in an IgA deficient 18q-- patient. The findings in these two patients suggest that gene(s) concerned with regulation of IgA synthesis are located on the distal long arm of chromosome 18 between 18q23 and qter.