Use of Leu M1 and antiepithelial membrane antigen monoclonal antibodies for diagnosing Hodgkin's disease. Issue 3 (March 1986)

• Record Type: Journal Article
• Authors: Jack, A S; Cunningham, D; Soukop, M; Liddle, C N; Lee, F D
• Is Part Of: Journal of clinical pathology. Volume 39:Issue 3(1986)
• Page Start: 267
• Page End: 270
• Publication Date: 1986-03
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.39.3.267
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Biopsies of 82 patients diagnosed as having Hodgkin's disease were reviewed. Seventeen were reclassified histologically as non-Hodgkin's lymphoma or reactive lymphoid hyperplasia. A substantial number of cases of Hodgkin's disease were negative when stained with Leu M1. Staining for Leu M1 was not found in the cases of non-Hodgkin's lymphoma or reactive lymphoid hyperplasia. With the exception of the lymphocyte predominant nodular subtype of Hodgkin's disease, epithelial membrane antigen staining was seen in a few cases of Hodgkin's disease and non-Hodgkin's lymphomas. This was not a useful discriminating feature.