Symptomatic intracranial hypertension during recovery from the syndrome of headache with neurologic deficits and cerebrospinal fluid lymphocytosis (HANDL). Issue 2 (3rd February 2017)

• Record Type: Journal Article
• Authors: Mulroy, Eoin; Yap, Joel; Danesh-Meyer, Helen; Anderson, Neil
• Is Part Of: Practical neurology. Volume 17:Issue 2(2017)
• Page Start: 145
• Page End: 148
• Publication Date: 2017-02-03
• Subjects: HEADACHE -- VISION -- MIGRAINE; Neurology -- Periodicals; 616.8005
• DOI: 10.1136/practneurol-2016-001539
• Languages: English
• ISSNs: 1474-7758

Abstract

Abstract : The syndrome of headache with neurologic deficits and cerebrospinal fluid lymphocytosis (HANDL) is rare; it comprises migrainous headaches (generally in headache-naïve people), fluctuating neurological symptoms and cerebrospinal fluid (CSF) lymphocytosis. The syndrome generally runs a benign, self-limiting course over weeks. A small proportion of patients develop intracranial hypertension as a consequence of the illness. Recurrence of headaches or development of visual symptoms following apparent recovery from HANDL should prompt urgent re-evaluation for elevated intracranial pressure. Short-to-medium term management with CSF drainage and acetazolamide may be necessary to prevent visual loss.